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CT结肠镜诊断结直肠肿瘤和息肉准确性的系统评价
引用本文:谭振刚,许海楠,孙旭. CT结肠镜诊断结直肠肿瘤和息肉准确性的系统评价[J]. 中华肿瘤防治杂志, 2011, 18(5): 361-366
作者姓名:谭振刚  许海楠  孙旭
作者单位:1. 中国人民解放军第二三零医院外五科,辽宁,丹东,118000
2. 中国医科大学临床医学七年制系,辽宁,沈阳,110001
摘    要:目的:系统评价CT结肠镜用于结直肠肿瘤和息肉诊断的临床价值。方法:通过计算机检索及手工查阅,全面收集CT结肠镜用于结直肠肿瘤和息肉诊断的中英文文献,按纳入与排除标准筛选文献并提取纳入研究中有关准确度的数据,根据QUADAS条目进行质量评价,采用Me-ta Disc 1.4软件检验研究间的异质性并进行Meta分析。结果:最终纳入英文文献22篇,中文文献0篇。异质性检验结果为Spearman相关系数=0.406,P=0.244,提示阈值效应引起的异质性较小,但是存在其他因素导致的异质性,按随机效应模型进行Meta分析。CTC结肠镜诊断结直肠肿瘤和息肉的敏感度和特异度分别为69%和83%,而且诊断的敏感度和特异度随着肿物大小的增加而增加,分别为62%~81%和90.1%~92.4%。结论:用CT结肠镜诊断结直肠肿瘤和息肉具有很高的特异性,但其敏感度波动范围很大。

关 键 词:CT结肠镜  结直肠肿瘤  结直肠息肉  Meta分析

Accuracy of computed tomographic colonography for the detection of polyps and colorectal tumors: A systematic review and Meta-analysis
TAN Zhen-gang,XU Hai-nan,SUN Xu. Accuracy of computed tomographic colonography for the detection of polyps and colorectal tumors: A systematic review and Meta-analysis[J]. Chinese Journal of Cancer Prevention and Treatment, 2011, 18(5): 361-366
Authors:TAN Zhen-gang  XU Hai-nan  SUN Xu
Affiliation:TAN Zhen-gang1,XU Hai-nan2,SUN Xu2 1.Department of General Surgery,No.230 Hospital of Chinese People's Liberation Army,Dandong 118000,P.R.China 2.Clinical Medicine of Seven-years,China Medical University,Shenyang 110001,P.R.China
Abstract:OBJECTIVE:To perform a meta-analysis of the diagnostic accuracy of computed tomographic colonography(CTC) for the detection of polyps and colorectal tumors.METHODS: A comprehensive electronic search and additional manual tracking were performed to retrieve relevant studies on CTC in diagnosis of polyps and colorectal tumors in English and Chinese.The data about the accuracy of the included studies were extracted for further heterogeneity studies;statistical pooling and SROC(summary receiver operating charac...
Keywords:computed tomographic colonography  colorectal neoplasms  colorectal polyps  Meta-analysis  
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