葛根芩连汤联合西药治疗小儿毛细支气管炎随机平行对照研究

[目的]观察葛根芩连汤联合西药治疗小儿毛细支气管炎疗效。[方法]使用随机平行对照方法,将80例门诊患者按随机数字表法分为两组。对照组40例氧疗、糖皮质激素及雾化吸入控制喘憋,抗感染等。治疗组40例葛根芩连汤(射干、炙麻黄各5g,葛根、黄芩、黄连各8g,白芍5g,五味子6g,炙甘草3g),1剂/d,水煎50~60mL,温水分服;痰多加前胡、瓜蒌、竹沥;咳剧加桔梗、杏仁、呕吐加半夏、竹茹;热甚加山栀。西医治疗同对照组。连续治疗3d为1疗程。观测临床症状、症状改善时间、不良反应。连续治疗5疗程,判定疗效。[结果]治疗组痊愈25例,有效15例,无效0例,痊愈率62.50%。对照组痊愈15例,有效24例,无效0例,痊愈率37.50%。但痊愈率治疗组优于对照组(P0.05)。各项症状改善时间治疗组少于对照组(P0.05)。[结论]葛根芩连汤联合西医治疗小儿毛细支气管炎效果显著,值得推广。

A Randomized Controlled Trial of Gegen Qinlian Decoction Combined with Western Medicine in the Treatment of Bronchiolitis

[ Objective ] Observed Gegenqinlian combined with western medicine pediatric bronchiolitis.[Methods] Random parallel control method, 80 outpatients were randomly divided into two groups. A control group of 40 patients oxygen therapy, inhalation corticosteroids and control asthmatic, anti-infection. Treatment group of 40 patients Gegenqinlian （ Shegan, Sunburn ephedra each 5g, arrowroot, baicalin, berberine each 8g, peony 5g, Schisandra 6g, licorice 3g）, 1 Preparation / d, decoction 50- 60mL, warm water service; sputum plus Peucedanum, melon, Zhu Li; cough drama plus bellflower, almonds, vomiting plus Breit, Zhuru;heat even add Gardenia. Western medicine with the control group. 3d is a continuous course of treatment. Observation of clinical symptoms, symptoms of time, adverse reactions. 5 continuous treatment regimen to determine efficacy. [ Results ] The treatment group cured 25 cases, effective 15 cases, invalid 0 cases, total effective rate was 100%, cure rate 62.50%. The control group cured 15 cases, effective 24 cases, invalid 0 cases, total effective rate was 100%, cure rate 37.50%. The treatment group is equivalent to the control group （P=0.05）, but the cure rate of the treatment group than the control group （P〈0.05） . The symptoms improved time in treatment group was less than that of the control group （P〈0.05） . [ Conclusion ] Western Gegenqinlian combined treatment of children with bronchiolitis effect is significant, it is worth promoting.