替米沙坦联合非洛地平治疗高血压疗效观察

目的：观察替米沙坦联合非洛地平治疗高血压的临床疗效。方法：将160例高血压患者随机分为治疗组与对照组,其中对照组80例,口服替米沙坦;治疗组80例,口服替米沙坦＋非洛地平,观察并随访6个月,分别在治疗1月、2月、3月和6月末测量患者的血压水平,评价降压达标率和不良反应。结果：两组患者的血压水平与治疗前相比均显著下降,经统计学分析,治疗组的降压达标率在1月末、2月末、3月末、6月末均高于对照组,P〈0.05,治疗组的不良反应发生率与对照组相比较无统计学差异,P〉0.05。结论：替米沙坦联合非洛地平治疗高血压临床疗效显著,可在临床推广使用。

Effect observation of telmisartan combined with felodipine in treatment of hypertension

Objective： To observe clinical efficacy of telmisartan combined with felodipine in treatment of hypertension.Methods： 160 patients with hypertension were randomly and equally divided into treatment group（80 cases） and control group（80 cases）,those in control group orally took telmisartan while those in treatment group orally took telmisartan combined with felodipine.They were observed and followed-up for 6 months.Blood pressure levels were measured 1,2,3 and 6 months after the treatment to assess the antihypertensive standard-reaching rate and side effects.Results： After the treatment,the blood pressure levels of the two groups both significantly decreased.Through the statistical analysis,the antihypertensive standard-reaching rates of treatment group 1,2,3 and 6 months after the treatment were all higher than those of control group（P 0.05）.At the same time,there was no significant difference in the incidence of side effects between the two groups（P 0.05）.Conclusions： Telmisartan combined with felodipine is an effective and safe way in the treatment of hypertension,and can be used prevalently.