11例喜炎平注射液致不良反应分析

目的:探讨使用喜炎平注射液后发生不良反应的特点及规律。方法:对11例使用喜炎平注射液后出现不良反应的患者的基本情况、原发疾病、不良反应发生情况进行分析。结果:喜炎平注射液所致11例不良反应患者女性较男性稍多,但没有统计学差异(P>0.05);不良反应患者中15岁以下的占8例,与其余年龄段相比,具有统计学差异(P<0.05);11例患者原发病均属于感染性疾病;不良反应出现在15～45min者占8例,与<15min组相比差异具有统计学意义(P<0.05);不良反应临床表现为全身反应(6例),皮肤及附件损害(3例),心血管系统损害(2例)。结论:喜炎平注射液致不良反应与患者性别无明显关系,不良反应多发生在15岁以下患者中,不良反应时间多出现在用药后30min左右,不良反应多表现为全身反应、皮肤及附件损害及心血管系统损害。

Analysis on 11 Cases of Adverse Drug Reaction by Xiyanping Injection

Objective：To explore the rules and causes of adverse reactions by using Xiyanping Injection.Methods：Analysing 11 patients＇ basic,primary disease,the incidence of adverse reactions who causing adverse drug reactions by Xiyanping Injection.Results：11 cases of Xiyanping injection adverse reactions in patients with women slightly more than men,but there is no statistical significant （P0.05）;Patients under 15 years of age accounted for 8 cases of adverse reactions in patients,the age of 15 to 60 accounted for 3 cases,with statistically significant （P 0.05）;11 patients＇ primary disease are infectious diseases;adverse reactions occur in 15min-45min accounted for 8 cases,compared to 15min group,the difference was statistical significant（P0.05）;clinical manifestations of adverse reactions included the systemic reactions （6 cases）,skin and appendages （3 cases）,cardiovascular system damage （2 cases）.Conclusions：Xiyanping injection adverse reactions caused no significant relationship with patients＇ gender,adverse reactions mostly occurred in patients under the age of 15,the adverse reaction time more appear in 30min after administration,adverse reactions more performance for the damage to the systemic reactions,skin and its appendages and cardiovascular system damage.