Two Cases of Lassa Fever Successfully Treated with Ribavirin and Adjunct Dexamethasone for Concomitant Infections |
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Authors: | Sylvanus Okogbenin,Cyril Erameh,Joseph Okoeguale,Osahogie Edeawe,Esele Ekuaze,Kelly Iraoyah,John Agho,Mirjam Groger,Benno Kreuels,Lisa Oestereich,Femi O. Babatunde,Peter Akhideno,Stephan Gü nther,Michael Ramharter,Till Omansen |
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Abstract: | Lassa fever is a viral hemorrhagic fever treated with supportive care and the broad-spectrum antiviral drug ribavirin. The pathophysiology, especially the role of hyperinflammation, of this disease is unknown. We report successful remission of complicated Lassa fever in 2 patients in Nigeria who received the antiinflammatory agent dexamethasone and standard ribavirin. |
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Keywords: | Lassa fever Lassa virus viruses ribavirin dexamethasone viral hemorrhagic fever Lassa mammarenavirus concomitant infections Nigeria |
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