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Prolonged remission of Epstein-Barr virus associated lymphoma secondary to T cell-depleted bone marrow transplantation
Authors:M P Lyttelton  P J Browett  M K Brenner  J D Norton  J L Kolman  J O McGee  S Hamilton-Dutoit  A V Hoffbrand  H G Prentice
Affiliation:Department of Haematology, Royal Free Hospital, London, UK.
Abstract:
High grade non-Hodgkin's lymphoma developed 42 days after allogeneic T cell-depleted bone marrow transplantation (BMT) for idiopathic aplastic anaemia. DNA hybridization studies confirmed clonality and incorporation of Epstein-Barr virus (EBV) genome. Prolonged remission followed low dose chemotherapy, local radiotherapy and early withdrawal of cyclosporin.
Keywords:
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