Prolonged remission of Epstein-Barr virus associated lymphoma secondary to T cell-depleted bone marrow transplantation |
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Authors: | M P Lyttelton P J Browett M K Brenner J D Norton J L Kolman J O McGee S Hamilton-Dutoit A V Hoffbrand H G Prentice |
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Affiliation: | Department of Haematology, Royal Free Hospital, London, UK. |
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Abstract: | High grade non-Hodgkin's lymphoma developed 42 days after allogeneic T cell-depleted bone marrow transplantation (BMT) for idiopathic aplastic anaemia. DNA hybridization studies confirmed clonality and incorporation of Epstein-Barr virus (EBV) genome. Prolonged remission followed low dose chemotherapy, local radiotherapy and early withdrawal of cyclosporin. |
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