| 山东省血友病患者乙型肝炎、丙型肝炎和人类免疫缺陷病毒感染情况调查分析 |
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| 引用本文： | 张雪芹,张心声,颜新,滕彬,房云海,程彦,安立. 山东省血友病患者乙型肝炎、丙型肝炎和人类免疫缺陷病毒感染情况调查分析[J]. 血栓与止血学, 2012, 18(4): 174-175,181 |
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| 作者姓名： | 张雪芹 张心声 颜新 滕彬 房云海 程彦 安立 |
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| 作者单位： | 1. 山东省血液中心山东省血友病诊疗中心,济南,250014
2. 山东省血液中心检验科 |
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| 摘 要： | 目的了解山东省血友病患者乙型肝炎病毒（HBV）、丙型肝炎病毒（HCV）和人类免疫缺陷病毒（HIV）的感染情况。方法对2005～2011年山东省血友病诊疗中心确诊或治疗的628例血友病患者进行HBsAg、抗-HCV和抗-HIV检测,并根据年龄段进行分组。结果 628例血友病患者HBsAg、抗-HCV和抗-HIV阳性率分别为3.3%（21/628）、9.6%（60/628）和0.6%（4/628）,总感染率为13.5%,不同年龄段患者HBsAg和抗-HCV阳性率有明显差异。结论山东省血友病患者乙型肝炎感染率低于一般人群,而丙型肝炎感染率高于一般人群,艾滋病感染有上升趋势,乙型肝炎和丙型肝炎感染与年龄密切相关。
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| 关 键 词： | 血友病 乙型肝炎病毒 丙型肝炎病毒 人类免疫缺陷病毒 |
The Survey and Anslysis of HBV, HCV and HIV Infecton in Hemophilia Patients of Shandong Province |
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| ZHANG Xue-qin , ZHANG Xin-sheng , YAN Xin , TENG Bin , FANG Yun-hai , CHENG Yan , AN Li. The Survey and Anslysis of HBV, HCV and HIV Infecton in Hemophilia Patients of Shandong Province[J]. Chinese Journal of Thrombosis and Hemostasis, 2012, 18(4): 174-175,181 |
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| Authors: | ZHANG Xue-qin ZHANG Xin-sheng YAN Xin TENG Bin FANG Yun-hai CHENG Yan AN Li |
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| Affiliation: | (Shandong center of Hemophilia Diagnosis and Treatment,Jinan,250014,China;*Blood Testing Department,Shandong Blood Center) |
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| Abstract: | Objective To better understand the infection of hepatitis B virus(HBV),hepatitis C virus(HCV) and human immunodeficiency virus(HIV) of hemophilia patients in Shandong.Methods Serum HBsAg,anti-HCV and anti-HIV were measured by ELISA,HIV infection was confirmed by Western Blotting method.Results The positive rates of HBsAg,anti-HCV and anti-HIV in 628 hemophilia patients were 3.3%,9.6% and 0.6%,respectively.Conclusion The prevalence of HBV infection in hemophilia patients was lower than natural population,the prevalence of HCV infection in hemophilia patients was even higher,the trend of HIV infection was increasing,the prevalence of HBV and HCV infection in hemophilia patients were closely correlated with age. |
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| Keywords: | Hemophilia HBV HCV HIV |
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