| 原发性肝癌的分子诊断标记物研究进展 |
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| 引用本文： | 王凯,高帅. 原发性肝癌的分子诊断标记物研究进展[J]. 分子诊断与治疗杂志, 2020, 0(1): 1-5,38 |
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| 作者姓名： | 王凯 高帅 |
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| 作者单位： | 山东大学齐鲁医院肝病科山东大学肝病研究所 |
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| 基金项目： | 国家科技重大专项(2018ZX10301406,2017ZX10202202) |
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| 摘 要： | 在我国,原发性肝癌具有较高的发病率和死亡率,严重威胁我国人民的生命和健康.对肝癌高危人群进行筛查,早期发现、早期诊断、早期治疗,是提高肝癌疗效的关键.肝癌特异性的血清分子诊断标记物是当前肝癌早期筛查的重要手段,已广泛应用于临床工作中.随着新的研究技术的不断应用和肝肿瘤发生机制认识的不断深入,有越来越多的原发性肝癌相关分...
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| 关 键 词： | 原发性肝癌 分子诊断 筛查 早期诊断 预后判断 |
Research progress of molecular diagnostic markers for primary hepatocellular carcinoma |
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| WANG Kai,GAO Shuai. Research progress of molecular diagnostic markers for primary hepatocellular carcinoma[J]. Journal of Molecular Diagnosis and Therapy, 2020, 0(1): 1-5,38 |
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| Authors: | WANG Kai GAO Shuai |
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| Affiliation: | (Department of Hepatology,Qilu Hospital of Shandong University,Hepatology Institute of Shandong University,Jinan,Shandong,China,250012) |
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| Abstract: | In China,primary liver cancer has a high morbidity and mortality,which seriously threatens the life and health of people.Screening of high⁃risk patients of liver cancer and detection,diagnosis and treatment at early stage are the keys to improving the treatment efficacy of hepatocellular carcinoma.Cancer⁃specific serum molecular diagnostic markers are an important method for early screening of hepatocellular carcinoma,and have been widely used in clinical practice.With the continuous application of new research techniques and the deepening understanding of the mechanism of liver tumorigenesis,more and more molecules related to hepatocellular carcinoma have been recognized and are expected to become markers for early diagnosis and prognosis of hepatocellular carcinoma.This article briefly reviews the research progress and potential clinical application value of molecular diagnostic markers for primary liver cancer in recent years. |
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| Keywords: | Hepatocellular carcinoma Molecular diagnosis Screening Early diagnosis Prognosis prediction |
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