中西医结合疗法对白内障超声乳化术后并发症的防治效果分析

目的:探讨中西医结合疗法对白内障超声乳化术后并发症防治的临床疗效。方法:96例白内障超声乳化术后患者随机分为观察组和对照组各48例。对照组60只眼,采用妥布霉素地塞米松眼膏,1次/4～6 h;普拉洛芬滴眼液,1次/2～4h;盐酸左氧氟沙星滴眼液,1次/2～4 h。共4周。观察组62只眼,在对照组的基础上加用自拟清肝明目方内服,1剂/d,共8周。于术后1 d,1,8,12,24周观察患者视力,前房反应,角膜内皮细胞计数,后发性白内障发生率及残余皮质吸收情况。结果:术后1,8,12及24周观察组视力恢复均优于对照组(P<0.01);术后1,8周观察组前房反应情况均轻于对照组(P<0.01);术后1,8,12及24周角膜内皮细胞数量均多于对照组(P<0.01);观察组术后8,12及24周后发性白内障发生率均低于对照组(P<0.05);观察组术后1,8,12及24周皮质吸收情况均明显优于对照组(P<0.05,P<0.01)。结论:采用中西医结合疗法能抑制白内障超声乳化术后前房反应,促进角膜内皮细胞的再生,促残余皮质吸收,减少后发性白内障发生率,促进视力的恢复。

Clinical Efficacy of Combined Therapy of Traditional Chinese Medicine and Western Medicine on Complications of Phacoemulsification

Objective: To explore the clinical efficacy of combined therapy of traditional Chinese medicine and western medicine on complications of phacoemulsification. Method: Ninety-six patients performed routine phacoemulsification surgery were randomly divided into observation group (n=48) and control group (n=48).There were 60 eyes in the control group, which were treated with bramycin dexamethasone oculentum (interval between application:4-6 h), pranoprofen eye drops(interval between application: 2-4 h) and levofloxacin hydrochloride eye drops (interval between application: 2-4 h) for 4 weeks.There were 62 eyes in the observation group, on the basis of the western medicines in control group, patients in the observation group were orally taken Qinggan Mingmu Fang, 1 dose daily for 8 weeks.The eyesight, anterior chamber reaction, corneal endothelial count, posterior capsule opacification incidence and the residual cortical absorption were observed at 1 d, 1, 8, 12, 24 weeks after surgery. Result: The recovery of eyesight in the observation group was better than the control group at 1, 8, 12, 24 weeks after surgery(P<0.01).The anterior chamber reaction in the observation group was lower than that in the control group at 1, 8 weeks after surgery(P<0.01).The corneal endothelial counts in the observation group were higher than the control group at 1, 8, 12, 24 weeks after surgery(P<0.01).The rate of occurrence of after-cataract in the observation group was lower than that in the control group at 8, 12, 24 weeks after surgery(P<0.05).The cortical absorption in the observation group was superior to the control group at 1, 8, 12, 24 weeks after surgery(P<0.05, P<0.01). Conclusion: Combination of Chinese and western medicine could suppress anterior chamber reaction after phacoemulsification, facilitate corneal endothelial cells regeneration, improve residual cortical absorption, decrease rate of occurrence of after-cataract and promote eyesight recovery.