| 胃肠癌患者血清及癌组织癌胚抗原的检测意义 |
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| 引用本文： | 吴荣,张敏,孙显露. 胃肠癌患者血清及癌组织癌胚抗原的检测意义[J]. 青岛大学医学院学报, 1990, 0(3) |
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| 作者姓名： | 吴荣 张敏 孙显露 |
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| 作者单位： | 青岛医学院病理解剖学教研室(吴荣，张敏)，青岛医学院附院医院病理科(孙显露) |
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| 摘 要： | 应用放射免疫测定法,对20例胃肠癌患者进行了血清癌胚抗原(CEA)测定,并应用免疫组化法对其中16例癌组织中的CEA进行了检测.检测结果,血清CEA阳性6例,癌组织CEA阳性9例.低分化癌的血清CEA显著高于高分化癌(P<0.05).血清CEA与癌灶部位、癌组织CEA与分化程度及血清CEA均无关(P>0.05).提示血清CEA的含量与癌组织的分化程度有关,血清CEA与癌组织内的CEA无平行关系.作者并对其机制及检测CEA的意义进行讨论.
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| 关 键 词： | 胃肠肿瘤 癌胚抗原 放射免疫测定 免疫酶技术 组织化学 |
THE SIGNIFICANCE OF CEA DETECTION IN SERUM AND TISSUE OF PATIENTS WITH GASTROINTESTINAL CARCINOMA |
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| Wu Rong,et al. THE SIGNIFICANCE OF CEA DETECTION IN SERUM AND TISSUE OF PATIENTS WITH GASTROINTESTINAL CARCINOMA[J]. Acta Academiae Medicinae Qingdao Universitatis, 1990, 0(3) |
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| Authors: | Wu Rong et al |
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| Affiliation: | Wu Rong,et al Department of Pathology |
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| Abstract: | The serum CEA levels were measured by radioimmunoassay in 20 patients with primary gastrointestinal carcinoma. 16 cases were stained for CEA in tissue sections by immunohistochemical technique. The results showed that there were 6 cases whose serum CEA levels were positive and 9 cases with positive tissue staining. Serum CEA levels were higher in poorly differentiated carcinoma than in highly differentiated type (P<0.05), but not related to the site of carcinoma, the degree of differentiation or the results of tissue CEA-staining (P>0.05). The possible mechanism and significance of CEA detection in gastrointestinal carcinomas are also discussed in this paper. |
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| Keywords: | Gastrointestinal neoplasms Carcinoembryonic antigen Radioimmunoassay Immunoenzyme technics Histocytochemistry |
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