Identification of human chorionic gonadotropin (HCG) secreting cells and other cell types using antibody to HCG and a new monoclonal antibody (mABlu-5) in cultures of human placental villi |
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Authors: | M. Frauli H. Ludwig |
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Affiliation: | (1) Department of Obstetrics and Gynecology, University of Basle, Switzerland;(2) Universitäts-Frauenklinik, Schanzenstrasse 46, CH-4031 Basle, Switzerland |
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Abstract: | Summary We have identified cells which secrete human chorionic gonadotropin (HCG) of cultures if first trimester placental villi. As a first step, we identified epithelial cells using a new monoclonal antibody. We then added HCG antibodies to the cultured cells. We found that syncytiotrophoblast (and not cytotrophoblast), Hofbauer cells and some mesenchymal cells stained with HCG antibodies. |
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Keywords: | HCG Monoclonal antibody lu-5 (mABlu-5) Cultures Human placenta |
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