| 检测CA199、CA125、CA153及CEA在肿瘤诊断中的意义 |
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| 引用本文： | 田满福,韩波.检测CA199、CA125、CA153及CEA在肿瘤诊断中的意义[J].临床和实验医学杂志,2010,9(7):483-485. |
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| 作者姓名： | 田满福 韩波 |
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| 作者单位： | 1. 内蒙古自治区赤峰市医院,内蒙古,赤峰,024000
2. 辽宁中医药大学附属医院,辽宁,沈阳,110032 |
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| 摘 要： | 目的探讨血清癌抗原199（CA199）、癌抗原125（CA125）、癌抗原153（CA153）和癌胚抗原（CEA）检测在对不同类型恶性肿瘤的诊断价值。方法采用全自动化学发光免疫分析法，检测62例不同类型肿瘤患者、14例非肺癌患者组及30例正常对照组血清CA199、CA125、CA153及CEA水平。结果胰腺癌患者组CA199、CEA水平显著高于对照组（P〈0．01、P〈0．05），CA199的阳性率达100％；胃癌患者组CA199、CA125、CA153、CEA水平显著高于对照组（P〈0．01或〈0．05）：乳腺癌组CA153、CA125、CA199水平均明显高于对照组（P〈0．01或〈0．05）；卵巢癌患者组CA125，CA153水平显著高于对照组（P〈0．01或P〈0．05）；肺癌患者组CA199，CA125及CEA水平明显高于非肺癌对照组及正常对照组（P均〈0．01）。CA199、CA125及CEA联检特异性92．9％、敏感性79．3％。结论CA199测定对胰腺癌的诊断提供可靠依据。CA199、CA125及CEA联合检测对肺癌的诊断有重要意义。CA199、CA125、CA153及CEA4项指标联检对胃癌和乳腺癌的诊断有一定价值。CA125、CA153对卵巢癌的诊断有一定价值。
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| 关 键 词： | 肿瘤标志物CA199 CA125 CA153 CEA |
The clinical value of the detections of CA199,CA125,CA153 and CEA in malignant tumors |
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| TIAN Man-fu,HAN Bo.The clinical value of the detections of CA199,CA125,CA153 and CEA in malignant tumors[J].Journal of Clinical and Experimental Medicine,2010,9(7):483-485. |
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| Authors: | TIAN Man-fu HAN Bo |
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| Institution: | TIAN Man-fu1,HAN Bo2.1 The Hospital of Chifeng,Chifeng,Inner Mongolia 024000,China,2. Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang Liaoning 110032 |
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| Abstract: | Objective To investigate the clinical value of serum CA199,CA125,CA153 and CEA detections in different types of malignant tumors.Methods Automatic chemiluminescence immunoassay was used to detect the serum level of CA199,CA125,CA153 and CEA in 62 patients with several types of tumors,14 patients with non-lung cancer and 30 healthy individuals.Results In comparison with the control group,the levels of CA199 and CEA were higher in patients with pancreatic cancer (P<0.01,P<0.05) and the positive rate of CA199 ... |
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| Keywords: | CA199 CA125 CA153 CEA |
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