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A case of parathyroid hormone-related peptide producing gallbladder carcinoma presenting humoral hypercalcemia of malignancy]
Authors:Yoshitaka Imoto  Naoki Muguruma  Tetsuo Kimura  Masako Kaji  Hiroshi Miyamoto  Seisuke Okamura  Susumu Ito  Masahiko Nakasono  Mitsuyoshi Hirokawa  Toshiaki Sano
Affiliation:Department of Digestive and Cardiovascular Medicine, University of Tokushima Graduate School.
Abstract:Humoral hypercalcemia of malignancy (HHM) in neoplastic syndrome has been most commonly reported in squamous cell carcinoma. Gallbladder carcinoma with HHM is uncommon. In this report, we describe a male case of gallbladder carcinoma with marked hypercalcemia and a high level of serum parathyroid hormone-related peptide (PTHrP). An immunohistochemical examination using PTHrP was also positive.
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