Extracorporeal membrane oxygenation in burn and smoke inhalation injury |
| |
Authors: | Sven Asmussen Dirk M. Maybauer John F. Fraser Kristofer Jennings Shane George Amar Keiralla Marc O. Maybauer |
| |
Affiliation: | 1. Department of Anesthesiology, The University of Texas Medical Branch and Shriners Burns Hospital for Children, Galveston, TX, USA;2. Department of Anaesthesiology and Intensive Care, Philipps University, Marburg, Germany;3. Critical Care Research Group, The University of Queensland and the Prince Charles Hospital, Brisbane, Australia;4. Department of Epidemiology and Biostatistics, The University of Texas Medical Branch and Shriners Burns Hospital for Children, Galveston, TX, USA;5. Department of Cardiothoracic Anaesthesia and Intensive Care, Oxford Heart Centre, Oxford University Hospitals, Oxford, UK |
| |
Abstract: | A systematic review and meta-analysis was conducted to assess the level of evidence for the use of extracorporeal membrane oxygenation (ECMO) in hypoxemic respiratory failure resulting from burn and smoke inhalation injury. We searched any article published before March 01, 2012. Available studies published in any language were included. Five authors rated each article and assessed the methodological quality of studies using the recommendation of the Oxford Centre for Evidence Based Medicine (OCEBM). Our search yielded 66 total citations but only 29 met the inclusion criteria of burn and/or smoke inhalation injury. There are no available systematic reviews/meta-analyses published that met our inclusion criteria. Only a small number of clinical trials, all with a limited number of patients, were available. The overall data suggests that there is no improvement in survival for burn patients suffering acute hypoxemic respiratory failure, with the use of ECMO. ECMO run times of less than 200 h correlate with higher survival compared to 200 h or more. Scald burns show a tendency of higher survival than flame burns. |
| |
Keywords: | ALI ARDS ECMO Meta-analysis Respiratory failure Systematic review |
本文献已被 ScienceDirect 等数据库收录! |
|