中医药治疗经间期出血的Meta分析 |
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引用本文: | 黎柳娇,;郑景辉.中医药治疗经间期出血的Meta分析[J].中医临床研究,2014(31):14-17. |
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作者姓名: | 黎柳娇 ;郑景辉 |
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作者单位: | [1]广西中医药大学2011级针灸推拿学桂派杏林师承班,广西南宁530001; [2]广西中医药大学附属瑞康医院,广西南宁530011 |
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摘 要: | 目的:系统评价中医药治疗经间期出血的疗效。方法:检索近8年中医药干预经间期出血的随机对照临床试验,并对文献结果进行Meta分析。结果:最终15篇临床研究文献入选,研究结果异质性检验:x2=14.93,P=0.38。故采用固定效应模型进行统计分析,合并后OR值为5.21,95%,可信区间为3.54~7.66,菱形位于中间线的右侧,经Z检验,Z=8.39,P〈0.00001,中医药治疗效果显著。“漏斗图”图形显示存在发表偏倚。结论:①中医药治疗经间期出血与西药治疗疗效相当,且可发挥其副作用少、安全性高的优势;②在有力证据方面,中医药(尤其针灸)治疗经间期出血需要更多高质量的研究文献,现阶段文献资料欠严谨。
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关 键 词: | 经间期出血 中医药 Meta分析 循证医学 |
A Meta-analysis of treating bleeding between periods in TCM medicine |
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Abstract: | Objective:To evaluate clinical efficacy of TCM medicine on bleeding between periods. Methods:Retrieving randomly controlled clinical trials of intervening bleeding between periods in TCM medicine in recent 8 years, and to Meta-analyze the literature result. Results:15 clinical research literature were selected, the results heterogeneity test:x2=14.93, P=0.38. Application of fixed-effects model for statistical analysis, the combined OR=5.21, 95%, CI:3.54~7.66, diamond on the right side of the middle line by the Z test, Z=8.39, P〈0.00001, TCM medicine shows remarkable effect. Funnel plot graph shows publication bias was presented. Conclusion:I TCM medicine effective shows good effects, few side effects and high safety. II TCM medicine (especially acupuncture) treatment of bleeding between periods needs more high-quality research literature as strong evidence. |
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Keywords: | Bleeding between periods TCM medicine Meta-analysis Evidence-based Medicine |
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