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急性心肌梗塞患者外周血活性T淋巴细胞亚群的研究
引用本文:王巍嵩,张志方,吕品,张春艳,李永勇. 急性心肌梗塞患者外周血活性T淋巴细胞亚群的研究[J]. 中国病理生理杂志, 1999, 15(5): 433-435
作者姓名:王巍嵩  张志方  吕品  张春艳  李永勇
作者单位:1. 暨南大学医学院第一附属医院心内科,广州,510632
2. 中山医科大学基础医学院
摘    要:
目的:研究15例急性心肌梗塞患者外周血淋细胞亚群和活性标志的变化。方法:流式细胞仪技术,结果:急性心肌梗塞患者外周血淋巴细胞CD3^+DR^+和CD4^+和DR^+百分率明显高于对照组。结论:急性心肌梗塞患者存在免疫功能紊乱,辅助性T淋巴细胞处于高活性状态。

关 键 词:心肌梗塞 HLA-DR抗原 T细胞亚群

Study of activated T-lymphocyte subsets of peripheral blood in patients with acute myocardial infarction
WANG Wei-Song,ZHANG Zhi-Fang,LU Pin,ZHANG Chun-Yan,LI Yong-Yong. Study of activated T-lymphocyte subsets of peripheral blood in patients with acute myocardial infarction[J]. Chinese Journal of Pathophysiology, 1999, 15(5): 433-435
Authors:WANG Wei-Song  ZHANG Zhi-Fang  LU Pin  ZHANG Chun-Yan  LI Yong-Yong
Abstract:
AIM: The peripheral blood T-lymphocytes subsets and its active markers in patients with acute myocardial infarction were studied.METHODS:Low cytometric analysis.RESULTS:The percentages of CD 3DR and CD 4DR T-lymphocytes and the ratio of CD 4DR /CD 8DR were significantly increased in patients with acute myocardial infarction. Where CD 8DR T-lymphocytes had no marked difference between normal controls and patients with acute myocardial infarction.CONCLUSION:The disturbance of activated T-lymphocyte subsets and the highly state of activated T-helper lymphocyte were found in patients with acute myocardial infarction.
Keywords:Myocardial infarction  Lymphocyte transformation  HLA-DR antigens  
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