黏液性交界性卵巢肿瘤临床特点及预后分析

 目的 探讨黏液性交界性卵巢肿瘤(mucinous borderline ovarian tumor,M-BOT)的临床特点与预后。方法 收集33例M-BOT患者的临床资料,分析患者的临床特征、影响预后的病理因素,并分析与肿瘤复发有关的危险因素。结果 33例中,57.6%(19/33)进行了根治性手术,42.4%(14/33)进行了姑息性手术。39.4%(13/33)进行了全面分期手术。随访70(10～130)个月,随访率87.9%,全部病例复发11例(33.3%,11/33),与肿瘤相关死亡2例(6.1%,2/33)。单因素分析显示患者FIGO分期、手术方式与复发有关(P<0.05),但多因素分析结果显示2因素均不是肿瘤复发的独立危险因素(95% CI:0.115~1.369 和0.763~11.93)。结论 M-BOT患者预后较好,进展期患者复发率高,对于有生育要求的早期患者,可以选择保守性手术。

Clinical features and prognosis of mucinous borderline ovarian tumors

Objective To explore the relationship between the clinical features and prognosis of mucinous borderline ovarian tumors (M-BOTs). Methods The clinical data on 33 patients with M-BOTs was collected before the clinical features, pathological factors affecting prognosis and risk factors for tumor recurrence were analyzed retrospectively. Results All the patients underwent surgery as the initial treatment, 19 of whom (57.6%) underwent a radical procedure, and 14 (42.4%) underwent conservative surgery. Of these 33 patients, 13 (39.4%) underwent a staging procedure. With an average follow-up of 70 months (ranging from 10 to 130 months), the follow-up rate was 87.9%. Tumor recurred in eleven of these patients (33.3%, 11/33) and 2 cases (6.1%, 2/33) died of tumor progression. Univariate analysis showed that FIGO staging and types of surgical procedures were factors that influenced recurrence (P<0.05), but multivariate analysis showed that advanced FIGO staging (95% CI 0.115-1.369; P>0.05) and conservative surgery (95% CI 0.763-11.93; P>0.05) were not independent risk factors. Conclusions The majority of patients with M-BOTs have a favorable prognosis. Recurrence is more likely in patients with later-stage disease. Conservative surgery can be an option for early-stage patients who hope to remain fertile.