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| 用正交试验设计优选苦参七味胶囊的提取工艺条件 | |
| 引用本文： | 孟永梅,韩额尔德木图,孟根杜希.用正交试验设计优选苦参七味胶囊的提取工艺条件[J].国际中医中药杂志,2010,32(6). |
| 作者姓名： | 孟永梅 韩额尔德木图 孟根杜希 |
| 作者单位： | 1. 内蒙古医学院蒙药研究所,呼和浩特,010059 2. 内蒙古医学院附院蒙医科,呼和浩特,010059 3. 内蒙古医学院蒙医方剂教研室,呼和浩特,010059 |
| 摘 要： | 目的 探索苦参七味胶囊的最佳提取工艺条件.方法 利用正交试验设计方案,以栀子苷和氧化苦参碱为测定指标,综合考察水提和乙醇提取制备工艺.结果 优选出工艺条件分别为:栀子等两味药加12倍量的水,提取2次,2h/次:苦参等四味药加12倍量的85%乙醇,提取3次,2 h/次,土木香粉碎过100目筛用于收膏.结论 本提取工艺方法简便,操作可行. |
| 关 键 词： | 苦参七味胶囊 正交设计 高效液相色谱法 提取工艺 |
Optimizing the conditions for extraction of Daoguleebusi-7 capsule by orthogonal experiments |
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| MENG Yong-mei,HAN Eerdemutu,Meng Genduxi.Optimizing the conditions for extraction of Daoguleebusi-7 capsule by orthogonal experiments[J].International Journal of Traditional Chinese Medicine,2010,32(6). | |
| Authors: | MENG Yong-mei HAN Eerdemutu Meng Genduxi |
| Abstract: | Objective To research the optimal conditions for extraction of Daoguleebusi-7 capsule. Methods A comprehensive investigation for the process of extraction by water and ethanol was made using orthogonal experiments.Results The optimal process conditions were: gardenia and another drug were added into 12 volumes of water, extracted 2 times and two hours per time; Sophorae Flavescentis and other four dugs were added into 12 volumes of 85% ethanol,extracted 3 times and two hours per time, elecampane was crushed and screened through 100 mesh sieve to electuary.Conclusion The extraction process is simple and feasible for operation. |
| Keywords: | Daoguleebusi-7 capsule Orthogonal Experiments Design HPLC Extraction process |
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