中国人优势大脑半球岛叶高分辨率MRI形态学研究#br#

［摘要］ 目的 利用MRI对不同年龄段中国人优势大脑半球岛叶进行测量，建立正常人岛叶脑沟、脑回的形态正常值标准，为多种岛叶精神疾病诊断提供影像诊断依据。 方法 选取75例健康志愿者，进行头部MRI扫描，测量并统计中国人优势大脑半球岛叶各亚回形态学数据，包括各亚回皮质、白质、脑沟宽度值，并对各年龄组形态学数据进行对比分析。 结果 横沟长度在各年龄组间差异有统计学意义（P＜0.05）；而其他优势大脑半球岛叶各亚回皮质、白质、脑沟宽度差异没有因年龄而发生显著变化（P＞0.05）。 结论 岛叶属于较低级别脑叶，其形态学参数受年龄影响较小，测量值稳定，故有可能成为较可靠的研究脑部精神疾病的指标。

High-resolution MRI morphology of dominant hemisphere insular lobe in Chinese population

［Abstract］ Objective To establish the normal values of insular lobe morphology in Chinese people, for diagnosing insular psychiatric diseases. Methods A total of 75 healthy volunteers were enrolled in the study. MRI of the head were performed to measure and analyze the morphological data of the subtropical lobes, including the subcortical, white matter, and sulcus width values. Morphological data was compared and analyzed. Results The length of transverse sulcus had significant difference among different age groups(P＜0.05). There was no significant difference in the width of subcortex, white matter and sulcus among the other dominant cerebral hemispheres(P＞0.05). Conclusion The insular lobe belongs to the lower level of brain lobe. Its morphological parameters are less affected by age and the measured values are stable. Therefore, it may be a reliable index for the study of brain mental disorders.