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Epidermodysplasia verruciformis and malignant thymoma |
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| Authors: | W.K. JACYK J.A. HAZELHURST L. DREYER M.A. COCCIA-PORTUGAL |
| Affiliation: | The Departments of Dermatology, University of Pretoria, Republic of South Africa;The Departments of Anatomical Pathology, University of Pretoria, Republic of South Africa;The Departments of Chemotherapy, University of Pretoria, Republic of South Africa |
| Abstract: | We describe a patient with a long history of skin lesions clinically and histologically consistent with epidermodysplasia verruciformis (EV) who developed malignant thymoma. HPV-9DNA was found in the macular lesion and HPV-4DNA and HPV-9DNA in the coexistent common warts. Thrombocytopenia and hypogamma-globulinaemia preceded the diagnosis of thymoma. Our patient seems to represent an example of an EV-like syndrome in immunodeficiency. |
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