| 确定电离辐射灭菌剂量方法的比较 |
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| 引用本文： | 李凤梅,钱思敏.确定电离辐射灭菌剂量方法的比较[J].中国消毒学杂志,1993,10(2):75-79. |
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| 作者姓名： | 李凤梅 钱思敏 |
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| 作者单位： | 北京师范大学低能核物理研究所，北京师范大学低能核物理研究所，北京师范大学低能核物理研究所，北京师范大学低能核物理研究所 北京 100875，北京 100875，北京 100875，北京 100875 |
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| 摘 要： | 对一次性使用的注射器和针头作了初始污染菌数和分离出的17种污染菌对辐射敏感性的测定。以初始污染菌数的最大值,最抗辐射菌的D_(10)值和灭菌保证水平按公式计算出的辐射灭菌剂量接近于按AAMIB_1法确定值。
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| 关 键 词： | D_10值 初始污染 电离辐射灭菌 灭菌剂量 |
COMPARISON OF DIFFERENT METHODS FOR DETERMINATION OF STERILIZING DOSAGE OF IONIZING RADIATION |
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| Li Fengmei Qian Simin Luo Ping Zhong Xinming.COMPARISON OF DIFFERENT METHODS FOR DETERMINATION OF STERILIZING DOSAGE OF IONIZING RADIATION[J].Chinese Journal of Disinfection,1993,10(2):75-79. |
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| Authors: | Li Fengmei Qian Simin Luo Ping Zhong Xinming |
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| Abstract: | Using disposable syringe and needle as examples, the sterilizing dosage of γ-radiation (SD) was calculated according to the following equation after measurement of their maximun bioburden (N_(0max)) and the maximun D_(10) value (D_(10max)) of the contaminating bacteria: SD=D_(10max)lg N_(0max)/SAL The result indicated that the sterilizing dosage for syringe ( N_(0mzx)=150cfu, D_(10max)=2.3 kGy, SAL=10~(-6)) was 18.8 kGy and that for needle (N_(0mzx)=100cfu, D_(10max)=2.3kGy, SAL=10~(-6)) was 18.4 kGy. These values approximated those measured with AAMI B_1 method (20.5 kGy for syringe and 19.1 kGy for needle). However, the measurement and calculation of the former method are simpler than the latter. |
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| Keywords: | D_(10) value bioburden sterilization by ionizing radiation sterilizing dosage |
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