Role of Cachexia and Fragility in the Patient Candidate for Cardiac Surgery |
| |
| Authors: | Calogera Pisano Daniele Polisano Carmela Rita Balistreri Claudia Altieri Paolo Nardi Fabio Bertoldo Daniele Trombetti Laura Asta Maria Sabrina Ferrante Dario Buioni Calogero Foti Giovanni Ruvolo |
| |
| Affiliation: | 1.Department of Cardiac Surgery, Tor Vergata University Hospital, 00133 Rome, Italy; (C.A.); (P.N.); (F.B.); (D.T.); (L.A.); (M.S.F.); (D.B.); (G.R.);2.Physical and Rehabilitation Medicine, Tor Vergata University of Rome, 00133 Rome, Italy; (D.P.); (C.F.);3.Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University of Palermo, 90133 Palermo, Italy; |
| |
| Abstract: | ![]()
Frailty is the major expression of accelerated aging and describes a decreased resistance to stressors, and consequently an increased vulnerability to additional diseases in elderly people. The vascular aging related to frail phenotype reflects the high susceptibility for cardiovascular diseases and negative postoperative outcomes after cardiac surgery. Sarcopenia can be considered a biological substrate of physical frailty. Malnutrition and physical inactivity play a key role in the pathogenesis of sarcopenia. We searched on Medline (PubMed) and Scopus for relevant literature published over the last 10 years and analyzed the strong correlation between frailty, sarcopenia and cardiovascular diseases in elderly patient. In our opinion, a right food intake and moderate intensity resistance exercise are mandatory in order to better prepare patients undergoing cardiac operation. |
| |
| Keywords: | frailty vascular aging age related syndrome sarcopenia malnutrition |
|
|
