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组织工程神经在修复周围神经缺损中的应用
引用本文:张鹏,林立新,唐胜建,王成琪. 组织工程神经在修复周围神经缺损中的应用[J]. 中华创伤骨科杂志, 2004, 6(11): 1280-1282
作者姓名:张鹏  林立新  唐胜建  王成琪
作者单位:261021,山东省潍坊市,解放军八九医院全军创伤骨科研究所
摘    要:周围神经缺损的修复与重建是当前神经领域的一大难题。目前,国内外学者已着力研究雪旺细胞和生物材料复合构建组织工程化人工神经,并将其与日益完善的显微外科技术结合起来,提高周围神经损伤的修复水平。本文结合国内外研究成果,对周围神经损伤修复的研究进行回顾,着重从组织工程方面阐述周围神经修复方法的现状与前景。

关 键 词:组织工程 显微外科 周围神经 神经再生 雪旺细胞
文章编号:1671-7600(2004)11-1280-03
修稿时间:2003-11-26

Application of tissue engineered nerve in repair of peripheral nerve defects
ZHANG Peng,LIN Li xin,TANG Sheng jian,WANG Cheng qi. Application of tissue engineered nerve in repair of peripheral nerve defects[J]. Chinese Journal of Orthopaedic Trauma, 2004, 6(11): 1280-1282
Authors:ZHANG Peng  LIN Li xin  TANG Sheng jian  WANG Cheng qi
Affiliation:ZHANG Peng,LIN Li xin,TANG Sheng jian,WANG Cheng qiDepartment of Orthopaedic and Traumalogy,89th Hospital of PLA,Weifang,Shangdong 261021,China
Abstract:Regeneration of injured peripheral nerve is one of the recent research focuses. Many inspiring achievements have been made in such fields as choice of seeding cell source and proliferation in vitro. It is hopeful that nerve regeneration may be enhanced by combining the new techniques with microsurgery. In this paper, design and fabrication principles, key technologies, various applications, and new directions in the field of tissue engineered nerve are introduced. Much of this paper is devoted to the discussion of tissue engineered nerve in repair of peripheral nerve injury.
Keywords:Tissue engineering  Microsurgery  Peripheral nerve  Nerve regeneration  Schwann cells
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