| 远程预缺血的心肌保护机制 |
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| 引用本文： | 施节娟,吕国义,邓迺封.远程预缺血的心肌保护机制[J].国际麻醉学与复苏杂志,2006,27(3):182-185. |
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| 作者姓名： | 施节娟 吕国义 邓迺封 |
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| 作者单位： | 天津医科大学第二医院麻醉科,300211;天津医科大学第二医院麻醉科,300211;天津医科大学第二医院麻醉科,300211 |
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| 摘 要： | Remote myocardial preconditioning can protect myocardiuln. Some bioactive substances released from noncardiac tissues which suffer from ischemia and reperfusion protects the heart by neuronal and humoral paths. Preconditioning at a distance can attenuate myocardial intracellular acidosis and Ca^2＋ overload, reduce neutrophil and platelet infiltration, protect mitochondrial function and reduce free radicals. This method is simple to apply and have some clinical value. In order to safely apply this method to clinic, a further study on the remote myocardial preconditioning and its mechanism is necessary.
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Mechanism of myocardial protection by remote myocardial preconditioning |
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| SHI Jie-juan,LV Guo-yi,DENG Nai-feng.Mechanism of myocardial protection by remote myocardial preconditioning[J].international journal of anesthesiology and resuscitation,2006,27(3):182-185. |
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| Authors: | SHI Jie-juan LV Guo-yi DENG Nai-feng |
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| Institution: | Department of Anesthesiology, 2 nd Hospital of Tianjin Medical University, Tianjin 300211, China |
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| Abstract: | Remote myocardial preconditioning can protect myocardium. Some bioactive substances released from noncardiac tissues which suffer from ischemia and reperfusion protects the heart by neuronal and humoral paths. Preconditioning at a distance can attenuate myocardial intracellular acidosis and Ca2+ overload,reduce neutrophil and platelet infiltration, protect mitochondrial function and reduce free radicals. This method is simple to apply and have some clinical value. In order to safely apply this method to clinic, a further study on the remote myocardial preconditioning and its mechanism is necessary. |
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| Keywords: | remote myocardial preconditioning neuronal path humoral path myocardial protection |
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