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| 肿瘤血管生成拟态研究新进展 | |
| 引用本文： | 刘文斌,许戈良,荚卫东. 肿瘤血管生成拟态研究新进展[J]. 医学综述, 2010, 16(7) |
| 作者姓名： | 刘文斌 许戈良 荚卫东 |
| 作者单位： | 1. 天津医科大学研究生院,天津,300070;安徽省立医院肝脏外科,合肥,230001 2. 安徽省立医院肝脏外科,合肥,230001 |
| 基金项目： | 国家自然科学基金面上项目，安徽省科技攻关重点项目，安徽省自然科学基金面上项目，安徽省高校自然科学研究重点项目，安徽省"115"产业创新团队--肝细胞癌转移复发研究团队资助项目，安徽省优秀青年科技基金资助项目 |
| 摘 要： | 血管生成拟态是指具有可塑性、侵袭性的肿瘤细胞所形成的非内皮细胞衬覆的微血管通道,其在体内显示为过碘酸席夫染色阳性和CD31染色阴性的图案,在体外三维培养体系中显示为管状或图案样的网络,其可能与肿瘤的侵袭转移潜能以及较差的临床预后有关。 |
| 关 键 词： | 血管生成拟态 肿瘤 细胞外基质 |
Recent Advances in Vasculogenic Mimicry |
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| LIU Wen-bin,,XU Ge-liang,JIA Wei-dong.. Recent Advances in Vasculogenic Mimicry[J]. Medical Recapitulate, 2010, 16(7) | |
| Authors: | LIU Wen-bin XU Ge-liang JIA Wei-dong. |
| Affiliation: | LIU Wen-bin1,2,XU Ge-liang2,JIA Wei-dong2.(1.Graduate School of Tianjin Medical University,Tianjin 300070,China,2.The Department of Hepatic Surgery,Anhui Provincial Hospital,Hefei 230001,China) |
| Abstract: | The ability of aggressive tumors to form nonendothelial tumor cell-lined microvascular channels is known as vasculogenic mimicry(VM).VM channels are revealed as periodic acid-Schiff-positive and CD31-negative patterns in vivo,and tubular structures and patterned networks in three-dimensional culture in vitro,which may be associated with the invasive and metastatic potential of tumor cells,as well as poor clinical outcome. |
| Keywords: | Vasculogenic mimicry Tumor Extracellular matrix |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |