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HCMV既往感染对大学生神经行为的影响
引用本文:Yang G,Li YQ,Jing CX,Bu CF,Gao J,Li Z,Lai LD,Zhu WW,Zhou TH. HCMV既往感染对大学生神经行为的影响[J]. 中华实验和临床病毒学杂志, 2011, 25(1): 57-59. DOI: 10.3760/cma.j.issn.1003-9279.2011.01.019
作者姓名:Yang G  Li YQ  Jing CX  Bu CF  Gao J  Li Z  Lai LD  Zhu WW  Zhou TH
作者单位:1. 暨南大学生命科学技术学院生物工程学系,广州,510632
2. 暨南大学医学院流行病学教研室
基金项目:国家自然科学基金,中国博士后科学基金
摘    要:
目的探讨巨细胞病毒(HCMV)既:往感染与大学生神经行为特征之间的关系。方法招募87名在校大学生,采用伯乐.神经行为测试评价系统(B.NES)进行测试,同时采血分离血清检测受试对象的HCMVIgG抗体,采用SPSS软件对B.NES测试结果进行统计分析。结果有76人既往感染过巨细胞病毒,11人未感染过,巨细胞病毒的感染率为87.36%。既往感染HCMV的大学生在情感状态测试的“忧郁沮丧”方面得分为8.89±6.60,低于未感染的大学生组(15.73±9.00),差异有统计学意义(P〈0.05);在情感状态测试的其他方面、学习记忆、感知与心理运动方面感染组和对照组均差异无统计学意义(P〉0.05)。结论既往感染HCMV与抑郁的情感状态水平的降低存在关联。

关 键 词:巨细胞病毒  感染  大学  神经行为学表现

The effects of human cytomegalovirus infection on college students' neurobehaviors
Yang Guang,Li Yue-qin,Jing Chun-xia,Bu Chen-feng,Gao Jin,Li Zhe,Lai Li-dan,Zhu Wei-wei,Zhou Tian-hong. The effects of human cytomegalovirus infection on college students' neurobehaviors[J]. Chinese journal of experimental and clinical virology, 2011, 25(1): 57-59. DOI: 10.3760/cma.j.issn.1003-9279.2011.01.019
Authors:Yang Guang  Li Yue-qin  Jing Chun-xia  Bu Chen-feng  Gao Jin  Li Zhe  Lai Li-dan  Zhu Wei-wei  Zhou Tian-hong
Affiliation:Department of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Abstract:
Objective To explore relevant between human cytomegalovirus (HCMV) infection and college students' neurobehaviors. Methods 87 college students were enlisted. They were tested with Bole.Neurobehavioral evaluation system ( B. NES) , and HCMV IgG antibody was detected after separation of serum. We analyzed the test results of B. NES by SPSS software. Results 76 college students were infected by HCMV in the past and 11 college students were not infected. The infected group scored 8.89 ± 6.60 in depression aspect of emotion state test, while control group got 15. 73 ± 9. 00. There was Significant difference between infection group and control ( P < 0.05 ). There were no significant differences in other aspects of emotion states, study and memory, perception and mental movement ( P > 0.05 ). Conclusion HCMV infection is associated with depression status.
Keywords:Cytomegalovirus  Infection  Universities  Neurobehavioral manifestations
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