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Management of nephrotoxicity of chemotherapy and targeted agents: 2020
Authors:Varsha Chiruvella  Pavan Annamaraju  Achuta K Guddati
Affiliation:1. Division of Hematology/Oncology, Georgia Cancer Center, Augusta University, Augusta, GA 30909, USA ; 2. Department of Medicine, Liberty University College of Medicine, Lynchburg, VA, USA
Abstract:Nephrotoxic effects of certain chemotherapeutic agents such as cisplatin and ifosfamide has been well documented and these effects are carefully managed by oncologists during their usage. The introduction of targeted agents has added a new challenge to cancer management as their nephrotoxic effects and associated management is in the process of being adopted by oncologists. This work is a compilation of side effects on the renal system due to various chemotherapeutic, immunotherapeutic and targeted agents followed by their recommended management.
Keywords:Nephrotoxicity   side effects   tumor lysis syndrome   acute kidney injury   chronic kidney disease
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