正电子发射计算机体层扫描-计算机断层扫描在诊断胃肠道恶性肿瘤中的临床应用

目的 分析18氟-脱氧葡萄糖-正电子发射型计算机体层扫描-计算机断层扫描仪（18F-FDGPET-CT）在胃肠道恶性肿瘤诊断及术后随访中的应用价值.方法 39例怀疑胃肠道恶性肿瘤的患者均行全身18F-FDG PET-CT检查,并经手术或术后病理结果及随访确诊.结果 18F-FDG PET-CT显像对胃肠道恶性肿瘤原发病灶检出的灵敏度、特异度均为100.0％,在胃癌中对于转移灶的灵敏度、特异度、准确度分别为80.0％（4/5）、90.9％（10/11）、87.5 ％（14/16）,对结直肠癌转移灶的灵敏度、特异度、准确度分别为88.9％（8/9）、92.9％（13/14）、91.3％（21/23）.PET-CT诊断胃癌局部淋巴结转移的灵敏度、特异度、准确度分别为50.0％（3/6）、90.0％（9/10）、75.0％（12/16）,诊断结直肠癌局部淋巴结转移的灵敏度、特异度、准确度分别为71.4％（5/7）、93.8％（15/16）、87.0％（20/23）.结论 18F-FDGPET-CT对胃肠道恶性肿瘤的术前诊断及分期有重要价值,优于传统检查方法.

Clinical application of positron emission tomography-computed tomography in the diagnosis of gastrointestinal tumors

Objective: To explore 18F-FDG PET-CT in the detection of malignant tumors of the gastrointestinal tract. Methods: 39 patients with gastrointestinal tumors who was diagnosed with operation, pathological examination, clinical and imaging follow-up undertake the whole-body 18F-FDG PET-CT. Results: The sensitivity and specificity were both 100.0% for primary malignant tumors. Gastric metastases sensitivity, specificity and accuracy were 80.0% (4/5), 90.9% (10/11), 87.5% (14/16), and the colorectal metastases sensitivity, specificity, accuracy of diagnostic results were 88.9% (8/9), 92.9% (13/14), 91.3% (21/23). The gastric cancer lymph node metastasis sensitivity, specificity and accuracy were 50.0% (3/6), 90.0% (9/10), 75.0% (12/16), in the diagnosis of colorectal local lymph node metastasis the sensitivity, specificity and accuracy were 71.4% (5/7), 93.8% (15/16), 87.0% (20/23). Conclusion: The 18F-FDG PET-CT imaging for gastrointestinal malignant tumor diagnosis and residual lesions recurrence or lesions metastases of detection is of important value and better than traditional examination methods.