High-density lipoprotein subfractions,apolipoproteins and antipyrine clearance in normal subjects |
| |
| Authors: | P. V. Luoma A. Rautio J. Steng»rd E. A. Sotaniemi J. Marniemi |
| |
| Affiliation: | (1) Clinical Research Unit, Department of Medicine, University of Oulu, Oulu, Finland;(2) Rehabilitation Research Centre of the Social Insurance Institution of Finland, Turku, Finland |
| |
| Abstract: | Summary Serum high density lipoprotein (HDL) subfractions HDL2 and HDL3, apolipoproteins, and plasma antipyrine clearance (AP-CL) rate, an index of liver microsomal enzyme activity, were determined in 21 healthy subjects. High HDL cholesterol and HDL2 cholesterol concentrations and HDL cholesterol/cholesterol and HDL2/HDL3 cholesterol ratios were associated with high AP-CL. Phenobarbital enhanced antipyrine elimination and increased the apolipoprotein A-I/A-II ratio. Subjects who had high AP-CL had a more antiatherogenic HDL subfraction and apolipoprotein profile than those with low AP-CL. |
| |
| Keywords: | antipyrine clearance apolipoproteins HDL A-I A-II B HDL2 cholesterol microsomal enzyme induction phenobarbital |
| 本文献已被 SpringerLink 等数据库收录！ |
|
