| 微囊藻毒素污染及其促肝癌作用研究进展 |
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| 引用本文： | 柳丽丽,钟儒刚,曾毅. 微囊藻毒素污染及其促肝癌作用研究进展[J]. 卫生研究, 2006, 35(3): 377-379 |
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| 作者姓名： | 柳丽丽 钟儒刚 曾毅 |
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| 作者单位： | 1. 北京工业大学生命科学与生物工程学院,北京,100022
2. 中国疾病预防控制中心病毒病预防控制所 |
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| 摘 要： | 淡水水体的富营养化导致了蓝藻水华的普遍发生,微囊藻毒素是由蓝藻的部分藻属产生的环肽化合物,具有毒性大、分布广、结构稳定等特性,从而成为水环境中的重要潜在危害物质。微囊藻毒素已被证明具有明显的肝毒性,是肝肿瘤的促进剂之一。本文就微囊藻毒素的污染现状、肝毒性作用及其促肝癌机制等方面的研究进展进行了综述。
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| 关 键 词： | 微囊藻毒素 肝毒性 肝癌 促癌作用 |
| 文章编号： | 1000-8020（2006）03-0377-03 |
| 收稿时间： | 2005-12-12 |
| 修稿时间： | 2005-12-12 |
Study progress on pollution and liver cancer promotion of microcystins |
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| Liu Li-li,Zhong Ru-gang,Zeng Yi. Study progress on pollution and liver cancer promotion of microcystins[J]. Journal of hygiene research, 2006, 35(3): 377-379 |
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| Authors: | Liu Li-li Zhong Ru-gang Zeng Yi |
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| Affiliation: | College of Life Sciences and Bioengineering, Beijing University of Technology, Beijing 100022, China |
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| Abstract: | Eutrophication of fresh water lakes and ponds has caused the occurrence of cyanobacteria. Microcystins(MCs)is a class of toxic cyclic heptapeptide, which may be produced by some strains of various blue-green algae. It has become potential hazardous material in aquatic environments for its toxic, distribution and stability. MCs has been showed to be extremely potent hepatotoxins and been viewed as a promoter of liver tumor. In this review, the pollution condition of MCs and its hepatotoxins as well as its mechanisms have been summarized. |
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| Keywords: | microcystins hepatotoxin liver tumor tumor promotion |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
