| 细胞色素C滴眼剂的制备及药效学 |
| |
| 引用本文： | 王思玲,刘颖,李德馨,王璞,李乐道,张景海.细胞色素C滴眼剂的制备及药效学[J].沈阳药科大学学报,2005,22(5):321-323. |
| |
| 作者姓名： | 王思玲 刘颖 李德馨 王璞 李乐道 张景海 |
| |
| 作者单位： | 1. 沈阳药科大学,药学院,辽宁,沈阳,110016
2. 沈阳药科大学,制药工程学院,辽宁,沈阳,110016 |
| |
| 摘 要： | 目的制备细胞色素C滴眼剂,并对其基本性质与对硒致白内障大鼠的抗白内障作用进行初步研究。方法对制得的滴眼剂进行pH与澄明度、黏度与渗透压及酶活力与药效学考察。结果与结论制剂各项指标符合2000年版《中华人民共和国药典》对滴眼剂的要求,且具有良好的抗白内障活性。
|
| 关 键 词： | 细胞色素C 滴眼剂 药物性质 抗白内障作用 |
| 文章编号： | 1006-2858(2005)05-0321-03 |
| 收稿时间： | 2004-09-30 |
| 修稿时间： | 2004年9月30日 |
Characterizations and anti-cataract effects on selenite-treated rats of cytochrome C eye drops |
| |
| WANG Si-ling,LIU Ying,LI De-xin,WANG Pu,LI Le-dao,ZHANG Jing-hai.Characterizations and anti-cataract effects on selenite-treated rats of cytochrome C eye drops[J].Journal of Shenyang Pharmaceutical University,2005,22(5):321-323. |
| |
| Authors: | WANG Si-ling LIU Ying LI De-xin WANG Pu LI Le-dao ZHANG Jing-hai |
| |
| Abstract: | Objective To prepare and study the properties of cytochrome C (Cyt C) eye drops,and to investigate its anti-cataract effect.Methods The prepared Cyt C eye drops were characterized by pH,clarity,voscosity and osmotic pressure.The activity of Cyt C in the eye drops was measured,and the anti-cataract effect was studied in a selenite-induced cataract rats.Results and Conclusions The prepared eye drops meet the requirements for an eye drop by 《pharmacopoeia of China (2000)》,and exhibit a good anti-cataract activity. |
| |
| Keywords: | cytochrome C eye drops drug properties anti-cataract effect |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
