仙桃市2012年药品不良反应报告分析

目的:分析仙桃市药品不良反应(ADR)发生情况,为临床合理用药提供参考。方法:对仙桃市ADR监测中心2012年报告数据进行回顾性分析。结果:共收集655份ADR报告,其主要来源于医疗机构,占99.4%;年龄≤10岁的儿童发生ADR比例最高,占29.3%,其次为年龄>60岁的老年人,占16.6%;静脉给药方式是引发ADR的重要途径,占86.2%;引起ADR最多的药品是抗感染类药,占66.0%,其次为中药制剂,占15.1%;ADR导致的临床表现多为皮肤及其附件损害。结论:应加强儿童和老年人等特殊人群的用药监测;加强抗感染类药物和中药注射液的临床应用管理,保障用药安全、有效。

Analysis of ADR Reports of Xiantao City in 2012

Objective To provide a reference for clinical administration by analyzing the adverse drug reports of Xiantao city. Methods The report data from Xiantao ADR Monitoring Center of 2012 were analyzed retrospectively. Results There were 655 ADR reports collected,which mainly came from medical institutions, accounting for 99.4%. Children aged lower＇ than 10 years old and elderly aged over 60 years old were the high risk population of ADR,accounting for 29.3% and 16.6%, respectively. The intravenous administration was the main approach of ADR, accounting for 86. 2%. Anti-infective drugs were the most drugs caused ADR,accounting for 66.0% ,following were Chinese herbal medicine,accounting for 15.1%. The clinical symptoms of ADR were manifested on skin and skin appendage. Conclusion Special populations such as chil- dren and the elderly should be especially monitored in using drugs, and the management of clinical application of anti-infec- tive drugs and Chinese medicine injection should be strengthened, so as to ensure the safety and effectiveness of drugs.