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Alveolar Macrophage Secretory Products Effect Type 2 Pneumocytes Undergoing Hypoxia-Reoxygenation

Authors:	Anton S. McCourtie MRCS Alexander S. Farivar MD Steven M. Woolley MRCS Heather E. Merry MD Patrick S. Wolf MD Brendan Mackinnon-Patterson BS John C. Keech MD Elizabeth FitzSullivan MD Michael S. Mulligan MD

Affiliation:	Department of Surgery, Division of Cardiothoracic Surgery, University of Washington Medical Center, Seattle, Washington

Abstract:

Keywords:	Abbreviations and Acronyms: AM, Alveolar macrophage CINC, Cytokine induced neutrophil chemoattractant ELISA, Enzyme linked immunosorbent assay EMSA, Electrophoretic mobility shift assay ERK1/2, Extracellular signal-regulated kinase FBS, Fetal bovine Serum H-R, Hypoxia/Reoxygenation IL-1β, Interleukin-1 beta JNK, c-Jun N-terminal kinase LIRI, Lung ischemia reperfusion injury MAPK, Mitogen-activated protein kinase MCP-1, Monocyte chemotactic protein-1 MHC, Major histocompatibility complex MIP-1α, Macrophage inflammatory protein-1 alpha MIP-2, Macrophage inflammatory protein-2 NFκB, Nuclear factor kappa B PAEC, Pulmonary artery endothelial cell PBS, Phosphate buffered saline PBST, Phosphate buffered saline with tween RPMI, Roswell Park Memorial Institute Media T2P, Type 2 pneumocyte TNF-α, Tumor necrosis factor alpha
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