Effect of dietary copper source (inorganic vs. chelated) on immune response,mineral status,and fecal mineral excretion in nursery piglets |
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Authors: | Peng Liao Xugang Shu Bie Tan |
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Affiliation: | 1. Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, People’s Republic of China;2. College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou, People’s Republic of China |
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Abstract: | This experiment was conducted to determine the effect of dietary supplementation with copper sulfate and cupreous N-carbamylglutamate chelate (NCG-Cu) on the growth performance, serum biochemical profile, immune response, tissue mineral distributions, and fecal excretion of minerals in nursery piglets. Eighteen healthy nursery piglets were randomly assigned to 3 dietary treatments consisting of no copper in either form (control), 650?g/t copper sulfate (650?g/t Cu) or 320?g/t NCG-Cu (320?g/t NCG-Cu) for 35 days. Pigs fed the 320?g/t NCG-Cu diet showed a significantly (P?0.05) elevated growth rate, feed conversion efficiency, IgA and IgM levels, and decreased diarrhea rate compared to those fed the 650?g/t Cu diet. Fecal copper (Cu) and zinc (Zn) were increased (P?0.05) when pigs were fed the 650?g/t Cu diets compared with those fed the 320?g/t NCG-Cu diets. Tissue Cu has limited effects on tissue mineral distribution, except for the distribution in the spleen and liver (P?0.05). These results indicated that 320?g/t NCG-Cu (chelated) was as effective as 650?g/t Cu (inorganic Cu) for stimulating growth and the immune response and reducing dietary fecal Cu excretion, thus reducing environmental pollution.Abbreviations: NCG: N-carbamylglutamate chelate; ADG: average daily gain; ADFI: average daily feed intake; F/G: feed to gain ratio; ALB: albumin; GLU: blood glucose; CREA: creatinine; ALP: alkaline phosphatase; ALT: alanine aminotransferase; AST: aspartate amino transferase; GLB: globulin; TC: total cholesterol; TP: total protein; urea: Urea; D-BIL: direct-acting-bilirubin; T-BIL: total bilirubin; UA: urate; CK: creatine kinase; LDH: lactate dehydrogenase; IgG: immunoglobulin G; IgA: immunoglobulin A; IgM: immunoglobulin M; C3: complement C3; LD: longissimus dorsi; ICP-OES: inductively coupled plasma optical emission spectrometry; AA: amino acid; GIT: gastrointestinal; Cu-Met: Cu-methionine; CP: crude protein; NDF: neutral detergent fiber; ADF: acid detergent fiber. |
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Keywords: | N-carbamylglutamate chelate copper source growth performance fecal cu excretion nursery piglets |
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