宫颈上皮内瘤变与宫颈癌中DNA甲基化状态的研究 |
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引用本文: | 谭秋芬,李锋,潘晓琳. 宫颈上皮内瘤变与宫颈癌中DNA甲基化状态的研究[J]. 国际肿瘤学杂志, 2009, 36(9). DOI: 10.3760/cma.j.issn.1673-422X.2009.09.018 |
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作者姓名: | 谭秋芬 李锋 潘晓琳 |
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作者单位: | 石河子大学医学院病理教研室,832002;石河子大学医学院病理教研室,832002;石河子大学医学院病理教研室,832002 |
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基金项目: | 国家重点基础研究发展规划(973计划) |
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摘 要: | DNA甲基化与肿瘤发生发展关系的研究越来越受到重视,目前大量研究发现多种基因的异常甲基化与官颈上皮内瘤变及宫颈癌相关.
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关 键 词: | 宫颈上皮内瘤样病变 宫颈肿瘤 DNA甲基化 |
DNA methylation in cervical intraepithelial neoplasia and invasive cervical cancer |
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Abstract: | The relationship between DNA methylation and tumor development gets more and more at-tention. It has been recently found that aberrant promoter methylation of various of genes may be associated with cervical intraepithelial neoplasia(CIN) and invasive cervical cancer. Now we review the research progress of DNA methylation in CIN andeervieal carcinoma. |
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Keywords: | Cervical intTaepithelial neoplasia Cervix neoplasms DNA methylation |
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