| 仙灵二至颗粒的质量标准研究 |
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| 引用本文： | 宋文慧,;李兴科,;李亚男,;刘春梅.仙灵二至颗粒的质量标准研究[J].西北药学杂志,2014(5):452-454. |
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| 作者姓名： | 宋文慧 ;李兴科 ;李亚男 ;刘春梅 |
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| 作者单位： | [1]陕西省人民医院,西安710068; [2]西安新通药物研究有限公司,西安710077; [3]西安葛兰新通制药有限公司,西安710077 |
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| 基金项目： | 西安市创新支撑项目（编号：ZX06007） |
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| 摘 要： | 目的建立仙灵二至颗粒的质量标准。方法采用TLC法对仙灵二至颗粒中墨旱莲和知母进行定性鉴别;应用HPLC法对仙灵二至颗粒中的淫羊藿苷进行含量测定。结果墨旱莲和知母的薄层鉴别方法专属性强,简单可行。淫羊藿苷进样量在1.33.8μg范围内呈良好的线性关系,r=0.999 9;平均回收率为99.4%(RSD=1.1%)。结论该方法稳定、准确、重复性好,可用于仙灵二至颗粒的质量控制。
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| 关 键 词： | 仙灵二至颗粒 淫羊藿苷 质量标准 高效液相色谱法 |
Study on the quality standard of Xianling Erzhi Granules |
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| Institution: | SONG Wenhui , LI Xingke , LI Ya＇nan , LIU Chunmei (1. Shaanxi Provincial People＇s Hospital, Xi＇an 710068, China ; 2. Xi＇an Xintong Pharmaceutical Research Limited Company, Xi＇an 710077,China;3. Xi＇an Gelan Xintong Pharmaceutical Limited Company, Xi＇an 710077,China) |
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| Abstract: | Objective To establish the quality standard for Xianling Erzhi Granules .Methods Eclipta prostrate L .and Anemarrhe-na asphodeloides Bge .were identified by TLC ;icraiin was determined by HPLC .Results Eclipta prostrate L .and Anemarrhena asphodeloides Bge .could be detected by TLC ;The linear range of icraiin was good in the range of 1 .3-3 .8 μg ,r=0 .999 9 .The average recovery of icraiin was 99 .4% （RSD=1 .1% ） .Conclusion The established methods are stable ,accurate and good repro-duceable .This study provides a method for the quality control of Xianling Erzhi Granules . |
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| Keywords: | Xianling Erzhi Granules icraiin quality standard HPLC |
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