拜糖平与二甲双胍治疗2型糖尿病的临床效果研究

目的探讨拜糖平与二甲双胍药物在治疗2型糖尿病患者中的应用效果。方法2017年3月—2019年5月,选取该院78例2型糖尿病患者作为研究对象,按照随机数字表法分为对照组39例(采用二甲双胍治疗),观察组39例(采用拜糖平治疗),比较两组患者的临床效果、不良反应以及血糖水平。结果对比患者临床治疗有效率差异有统计学意义(P<0.05)。对照组患者空腹血糖水平、餐后2 h血糖水平,均明显高于观察组(P<0.05)。对照组患者不良反应发生率为28.21%,明显高于观察组5.13%(P<0.05)。结论通过对比拜糖平与二甲双胍药物在治疗2型糖尿病患者中的应用效果,结果证实,与二甲双胍药物相比,拜糖平药物能够减少不良反应的发生,改善其血糖水平,提高临床治疗效果,临床应用价值及临床推广极高。

The Clinical Effect of Acarbose and Metformin in the Treatment of Type 2 Diabetes

Objective To explore the application effect of Acarbose and metformin in the treatment of patients with type 2 diabetes.Methods From March 2017 to May 2019,78 patients with type 2 diabetes in the hospital were selected as the research subjects.According to the random number table method,39 patients in the control group(treated with metformin)and 39 patients in the observation group(treated with Acarbose),to compare the clinical effects,adverse reactions and blood glucose levels of the two groups of patients.Results There was a statistically significant difference in clinical treatment effectiveness between patients(P<0.05).The fasting blood glucose level and 2 h postprandial blood glucose level in the control group were significantly higher than those in the observation group(P<0.05).The incidence of adverse reactions in the control group was 28.21%,which was significantly higher than the observation group 5.13%(P<0.05).Conclusion By comparing the application effect of Baitangping and metformin in the treatment of patients with type 2 diabetes,the results confirm that compared with metformin,Acarbose can reduce the incidence of adverse reactions,improve its blood glucose level,and improve the clinical treatment effect,improve clinical application value and clinical promotion.