梅毒抗体检测方法的对比分析

目的：探讨梅毒抗体检测方法并进行对比分析。方法：选自2009年2月～2010年2月我院住院和门诊诊断和治疗的梅毒患者129例，采用TRUST、TP—ELISA、TPPA，3种梅毒血清学检测方法结果进行观察。结果：在3种方法检测的129例梅毒患者中，TRUST法检测阳性92例，阳性率为71．37％；TP—ELISA法检测阳性112例，阳性率为86．82％：TPPA法检测阳性129例，阳性率为100％。3种方法检测阳性率经统计学分析比较，P〈0．05有显著性差异。结论：进行大量人员的高危人群梅毒筛查时宜采用TP—ELISA检测方法；对TRUST和TP—ELISA等初筛阳性以及潜伏期梅毒和一些非螺旋体试验阴性又高度怀疑为梅毒患者的确认试验采用TRUST检测方法。

Comparison analysis of syphilis antibody

Objective： To analyse the detection methods of syphilis antibodies. Methods： 129 cases of syphilis inpatient and outpatient in our hospital were selected in February 2009-February 2010, with TRUST, TP-ELISA, TPPA, three kinds syphilis serological detection methods to observe the results. Results： 129 cases of syphilis with 3 methods of detection, with TRUST 92 cases were detected positive, the positive rate of 71.37%; TP-ELISA assay positive for 112 cases, the positive rate of 86.82%; TPPA positive for 129 cases, the positive rate of 100%. Three kinds of positive rates detected by statistical analysis and comparison of P〈0.05 were significant difference. Conclusion： The large number of persons at high risk for syphilis screening of easy use TP-ELISA detection. Of the TRUST and TP-ELISA and other screening positive, and latent syphilis spirochete test and some non-negative and highly suspected in patients with confirmed syphilis testing by TRUST detection.