社区获得性肺炎抗菌药物成本-效果分析

目的探讨3种抗菌药物治疗社区获得性肺炎的成本-效果。方法 63例社区获得性肺炎随机分为A、B、C组各21例,A组采用头孢哌酮舒巴坦治疗;B组采用阿莫西林舒巴坦治疗;C组采用阿奇霉素治疗。比较各组临床疗效,并进行成本-效果分析。结果 A、B组总有效率高于C组,A组高于B组,差异均有统计学意义(P<0.05)。以C组为对照,A组△C/△E为55.0,B组为40.1。结论阿莫西林舒巴坦为治疗社区获得性肺炎的最佳方案。

Cost - effectiveness analysis of antibiotic in treatment of community-acquired pneumonia

Objective To analyze the cost-effectiveness of 3 kinds of antibiotic in treatment of community-acquired pneumonia. Methods 63 cases of community-acquired pneumonia were randomly divided into group A,B,and C （21 cases in each ） , group A was treated with cefoperazone sulbacta/n;group B with amoxicillin;group C was treated with azithromycin. Clinical effect in the 3 groups were compared, and the cos!-effectiveness was analyzed. Results Total effect rates in group A and B were higher than those in group C, and group A was higher than group B, and the differences were statistically significant （ P 〈 0.05 ）. Group C was regarded as control, △C/△E of group A was 55. 0, and 40. 1 of group B. Conclusion Amoxicillin in treatment of community-acquired pneumonia is the best solution.