| 2,3,7,8-四氯苯二噁英宫内暴露对子鼠肾细胞及其亚细胞结构的毒性影响 |
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| 引用本文： | 袁红海,潘三强,宿宝贵,李素梅,康举龄. 2,3,7,8-四氯苯二噁英宫内暴露对子鼠肾细胞及其亚细胞结构的毒性影响[J]. 解剖学研究, 2011, 33(5): 321-322,330 |
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| 作者姓名： | 袁红海 潘三强 宿宝贵 李素梅 康举龄 |
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| 作者单位： | 1. 暨南大学医学院人体解剖学教研室,广东 广州,510632
2. 暨南大学附属第一医院 |
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| 摘 要： | 目的 探讨妊娠早期母鼠接触2,3,7,8-四氯苯二噁英(TCDD)后对子代新生鼠肾的毒性影响.方法 妊娠13d的SD雌性大鼠随机分为对照组、玉米油组和染毒组(每组6只),观察3组大鼠出生3d雌性鼠的肾细胞及其亚细胞结构差异.结果 对照组子鼠和玉米油组子鼠的肾,不论是细胞结构还是亚细胞结构均未见病理改变.染毒组中,5 n...
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| 关 键 词： | 2,3,7,8-四氯苯二噁英 宫内暴露 肾 |
ffects of intrauterine exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin on cell and subcellular morphology in neonatal rats |
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| YUAN Hong-hai , PAN San-qiang , SU Bao-gui , LI Su-mei , KANG Ju-ling. ffects of intrauterine exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin on cell and subcellular morphology in neonatal rats[J]. Anatomy Research, 2011, 33(5): 321-322,330 |
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| Authors: | YUAN Hong-hai PAN San-qiang SU Bao-gui LI Su-mei KANG Ju-ling |
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| Affiliation: | YUAN Hong-hai,PAN San-qiang,SU Bao-gui,LI Su-mei,KANG Ju-ling.Medical School and First Hospital of Jinan University,Guangzhou 510632,China |
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| Abstract: | Objective To study toxic effect of introuterine exposure TCDD in early pregnancy on renal structure in neonatal rat.Methods The pregnant 13 d SD rats were divided into randomly comtrol,cornoil,and toxied group.The light and electron microscopy were used to observate cell and subcelluar structue of kidney in neonatal rats.Results There were no found any pathological feature in control and corn oil group rats.In toxied group,renal unit was clearly seen but renal tubule expansion and mitochondrion swelling wer... |
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| Keywords: | 2 3 7 8-tetrachlorodibenzo-p-dioxin(TCDD) Intrauterine exposure Renal structure |
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