| 大黄对IL—1和IL—2产生的影响 |
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| 引用本文： | 王运平,李波清.大黄对IL—1和IL—2产生的影响[J].滨州医学院学报,1998,21(3):221-222. |
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| 作者姓名： | 王运平 李波清 |
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| 作者单位： | 胶南市第四人民医院 |
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| 摘 要： | 目的；检测大黄水提取物对ＩＬ－１和ＩＬ－２产生的影响，以研究大黄的免疫抑制作用机理。方法：将小鼠分实验组与对照组，大黄水提取物灌胃后，用胸腺细胞增殖法和脾淋巴细胞增殖法检测ＩＬ－１和ＩＬ－２。结果：与对照组相比，实验组ＩＬ－１和ＩＬ－２产生能力明显下降。结论：大黄的免疫抑制作用与其抑制ＩＬ－１和ＩＬ－２的产生有关。
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| 关 键 词： | 大黄 IL－1 IL－2 大鼠 药理 中药 |
THE EFFECT OF RHEUM OFFICINALE BAILLON ON THE PRODUCTION OF IL 1 AND IL 2 |
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| Wang Yunping,Li Boqing,Ding Guihua,et al.THE EFFECT OF RHEUM OFFICINALE BAILLON ON THE PRODUCTION OF IL 1 AND IL 2[J].Journal of Binzhou Medical College,1998,21(3):221-222. |
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| Authors: | Wang Yunping Li Boqing Ding Guihua et al |
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| Abstract: | Objective :To examine the effect of water extract of Rheum Officinale Baillon(ROB) on the production of IL 1 and IL 2,and study the mechanism of immunosuppression of ROB. Methods :The mice were divided into control and test groups.After the stomach was filled with water extract of ROB,the IL 1 and IL 2 were tested by thymocyte proliferation method and spleen lymphocyte proliferation method. Results :Compared with control group,production of IL 1 and IL 2 in test group decreased significantly. Conclusion: Immunosuppressive effect of ROB is correlated with its inhibition of IL 1 and IL 2 production. |
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| Keywords: | Rhubarb IL 1 IL 2 rat |
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