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氩激光光凝后兔视网膜电流图与脂质过氧化反应
引用本文:府卫平,蔡用舒.氩激光光凝后兔视网膜电流图与脂质过氧化反应[J].解放军医学杂志,1992,17(6):440-442.
作者姓名:府卫平  蔡用舒
作者单位:第四军医大学西京医院眼科 (府卫平,蔡用舒,惠延年),第四军医大学西京医院眼科(郭守一)
基金项目:国家自然科学基金(3870822)
摘    要:

关 键 词:氩激光  眼损伤  视网膜电图

ELECTRORETINOGRAPHY AND RETINAL LIPID PEROXIDATION AFTER ARGON LASER PHOTOCOAGULATION IN RABBITS
Fu Weiping,Cai Yongshu. Hui yannian,Guo Shouyi.ELECTRORETINOGRAPHY AND RETINAL LIPID PEROXIDATION AFTER ARGON LASER PHOTOCOAGULATION IN RABBITS[J].Medical Journal of Chinese People's Liberation Army,1992,17(6):440-442.
Authors:Fu Weiping  Cai Yongshu Hui yannian  Guo Shouyi
Institution:Fu Weiping,Cai Yongshu. Hui yannian,Guo Shouyi. Xijing Hospital,Fourth Military Medical University,Xi-an
Abstract:Electroretinogram (ERG) and retinal malondialdehyde (MDA) contents were measured after argon laser photocoagulation of the rabbit retina, in order to correlate ERG to MDA levels, and to assess the effects of superoxide dismutase (SOD) and Salvia miltiorrhia (Bunge) in the treatment. Thirty-three rabbits were divided randomly into normal, control, SOD and Salvia miltiorrhia (Bunge) treatment groups. The MDA levels at 4 h, 1 and 3 d after laser photocoagulation were significantly higher than that in normal group, but it returned to the normal level 7 d after laser injury. The MDA levels in either SOD or Salvia miltiorrhia group was significantly lower than that in controls 1 d alter injury. ERG b wave ratio in each treatment group was significantly increased when compared with the control 3 d after laser injury. These results suggest that ERG can be used for evaluation of laser retinal injury and assessment of the effects of drugs for treatment.
Keywords:Argon laser  Eye injury  Electroretinography  Retinal lipid
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