维生素A在鼠类雄性生殖中的作用

维生素A对视觉及多种细胞的生长与分化起到基础作用。在鼠类中，它与睾丸的功能调节有关。过量的维生素A使生精紊乱。维生素A缺乏导致生精停滞。维生素A受体突变小鼠不育。本文将从维生素A受体在睾丸中的分布、代谢及其对胚胎和成体睾丸功能的影响等方面概述其重要作用。

Functions of Retinoids in Reproduction of Male Murines

Objective In addition to a fundamental role in very diverse processes such as vision and growth and differentiation of numerous types of cells,vitamin A(retinol) is involved in the regulation of testicular functions in rats and mice.An excess of vitamin A leads to spermatogenetic disorders,and its deficiency induces early cessation of spermatogenesis.Furthermore,mouse mutant are steriles.In this review,the location of retinoic acid receptors,the metabolisms of action in the testis and its effects on fetal and adult testis are summarized.