Organic anion transport is the primary function of the SLC17/type I phosphate transporter family |
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Authors: | Reimer Richard J Edwards Robert H |
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Affiliation: | (1) Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA;(2) Departments of Neurology and Physiology, Graduate Programs in Neuroscience and Cell Biology, University of California, San Francisco, CA 94143, USA |
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Abstract: | Recently, molecular studies have determined that the SLC17/type I phosphate transporters, a family of proteins initially characterized as phosphate carriers, mediate the transport of organic anions. While their role in phosphate transport remains uncertain, it is now clear that the transport of organic anions facilitated by this family of proteins is involved in diverse processes ranging from the vesicular storage of the neurotransmitter glutamate to the degradation and metabolism of glycoproteins. |
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Keywords: | Neurotransmitter transporter Organic anion transport Sialin Type I phosphate transporter Vesicular glutamate transporter |
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