肝胆管囊腺癌的诊断及治疗

目的 探讨肝胆管囊腺癌的临床特征及其诊治方法。方法 回顾性分析6例肝胆管囊腺癌的临床资料。结果 6例中5例误诊为肝囊肿，1例误诊为肝脓肿。经病理学检查确诊后，5例行根治性切除术，其中2例分别于术后5年、7年死于复发；2例分别随访16、21个月，未见复发；1例于术后34个月出现肝内复发，继续随访4个月，现一般状态尚可；另1例因全身情况较差未能行根治性切除术者，仍在接受姑息性治疗。结论 肝胆管囊腺癌缺乏特异性临床特征，诊断主要依靠影像学和病理学检查，早期行根治性切除术是治疗的关键。

The diagnosis and treatment of intrahepatic biliary cystadenocarcinoma

Objective To investigate the clinical features, diagnosis and treatment of intrahepatic biliary cystadenocarcinoma. Methods The clinical data of six patients with intrahepatic biliary cystadenocarcinoma were analyzed retrospectively. Results Among these six cases, five were misdiagnosed as hepatic cyst and one as hepatic abscess. Radical resection was performed on five patients after definite diagnosis made by pathological examination. Two died of recurrence after 7 and 5 years respectively. The other two cases were followed up for 16 and 21 months respectively without an evidence of recurrence. One case with intrahepatic tumor recurrence after 34 months was followed up for up to 4 months. The poor risk patient who received palliative therapy was on a close follow-up. Condusions The diagnosis of intrahepatic biliary cystadenocarcinoma, without specific clinical feature, mainly depends on imaging and pathological examination. Early radical excision is the key of successful treatment.