| 蛋白质组学技术在癌症相关研究中的应用 |
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| 引用本文： | 眭维国,黄礼玲,陈洁晶,黄河,戴勇. 蛋白质组学技术在癌症相关研究中的应用[J]. 医学综述, 2008, 14(23): 3596-3599 |
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| 作者姓名： | 眭维国 黄礼玲 陈洁晶 黄河 戴勇 |
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| 作者单位： | 中国人民解放军第一八一医院中心实验室,广西,桂林,541002 |
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| 摘 要： | 寻找理想的表型生物标志物,阐明疾病发生、发展过程中起关键作用的蛋白质分子以用于癌症的早期检测诊断及预后评估一直是癌症研究领域的热点和难点。随着人类基因组测序的完成,癌症研究的重点从基因组学转移到蛋白质组学研究中,癌症研究中的差异蛋白质组学技术也飞快发展,极大推动了与癌症相关的差异蛋白质组学研究,本文综述了近年来蛋白质组学技术在与癌症相关研究中的一些应用。
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| 关 键 词： | 蛋白质组学 癌症 蛋白质微阵列 质谱 表面等离子共振 |
Proteomics Technology Application in Cancer Comparative Research |
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| SUI Wei-guo,HUANG Li-ling,CHEN Jie-jing,HUANG He,DAI Yong. Proteomics Technology Application in Cancer Comparative Research[J]. Medical Recapitulate, 2008, 14(23): 3596-3599 |
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| Authors: | SUI Wei-guo HUANG Li-ling CHEN Jie-jing HUANG He DAI Yong |
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| Affiliation: | Laboratory of the Center of Guangzhou Military Area Command;181th Hospital of PLA;Guilin 541002;China |
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| Abstract: | To look for the ideal phenotype biomaker,elucidate key functional protein in disease process,that use for early diagnosis detection and prognosis evaluation are hot topic and nodus in field of cancer research.With the human genome sequence determined,the filed of cancer research is moving beyond genomics to proteomics,and the comparative strategies involving in the cancer proteomic research have been developed,all these will accelerate the cancer proteomic research.In this review,we focused on proteomic tec... |
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| Keywords: | Proteomic Cancer Protein microarray Mass spectrum Surface plasmon resonance |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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