(1) Department of Neurology, E. J. Meyer Memorial Hospital, 14215 Buffalo, N. Y., USA;(2) Department of Pathology, the State University of New York at Buffalo, 14215 Buffalo, N. Y., USA
Abstract:
Summary Two cases of McArdle's syndrome are reported. One is a classical exaple; the other is unusual because of the in vitro presence of muscle phosphorylase activity. In the latter case. the electronmicroscopic investigation confirmed the diagnosis.The fine structural changes characteristic of this disease are summarized and it is concluded that histochemical studies alone are insufficient to exclude the diagnosis of McArdle's myopathy.