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Indinavir alters sterol and fatty acid homeostatic mechanisms in primary rat hepatocytes by increasing levels of activated sterol regulatory element-binding proteins and decreasing cholesterol 7alpha-hydroxylase mRNA levels
Authors:Williams Kris  Rao Yi Ping  Natarajan Ramesh  Pandak W Michael  Hylemon Phillip B
Affiliation:Department of Microbiology and Immunology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, VA 23298, USA.
Abstract:
Keywords:CYP7A1, cholesterol 7α-hydroxylase   HMG-CoA reductase, 3-hydroxy-3-methylglutaryl-Coenzyme A reductase   LDL-R, low density lipoprotein receptor   CYP27, sterol 27-hydroxylase
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