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Gallbladder Metastasis of Renal Cell Carcinoma: Report of Two Cases
Authors:Tatsuya Aoki  Keiichiro Inoue  Akihiko Tsuchida  Toshiaki Aoki  Kazuhiko Kasuya  Keiichi Kitamura  Yasuhisa Koyanagi  Tohru Shimizu
Affiliation:(1) Departments of Surgery and, JP;(2) Surgical Pathology, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan, JP
Abstract:We report two extremely rare cases of metastasis to the gallbladder from renal cell carcinoma. In both men, aged 63 and 80 years, a pedunculated polypoid gallbladder tumor was incidentally found 27 and 8 years after surgery for renal cell carcinoma, respectively. The tumors showed hypervascularity on diagnostic imaging. A histopathological examination showed no tumor cells in the gallbladder mucosa, but clear cell carcinoma was predominantly observed below the mucosal layer. Furthermore, based on various specific and immunohistochemical studies as well as the electron-microscopic findings, the patients were pathologically diagnosed to have gallbladder metastasis of renal cell carcinoma. Received: February 16, 2001 / Accepted: September 11, 2001
Keywords:Gallbladder metastasis  Renal cell carcinoma  Clear cell carcinoma
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