小剂量蕲蛇酶联合足量胰岛素治疗肥胖中青年的2型糖尿病 |
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引用本文: | 郭凯霞,朱兆恩,高华,许志华,高长庆. 小剂量蕲蛇酶联合足量胰岛素治疗肥胖中青年的2型糖尿病[J]. 实用医药杂志(山东), 2005, 22(10): 868-870 |
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作者姓名: | 郭凯霞 朱兆恩 高华 许志华 高长庆 |
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作者单位: | [1]155医院,河南开封475003 [2]河南大学医学院,河南开封475000 |
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基金项目: | 军区“十五”重点科研课题,序号02z33 |
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摘 要: | 目的探讨改善微循环药物联合足量胰岛素注射,恢复和/或增强胰岛素敏感性的方法以及治疗肥胖中青年2型糖尿病的疗效。方法接受小剂量蕲蛇酶联合足量胰岛素注射为试验组,口服二甲双胍联合小剂量胰岛素注射为对照组。比较两组患者治疗前后的11项临床指标。结果试验组治疗后与胰岛素敏感性有关的7项指标和4项伴随表现指标与对照组比较有显著性差异(P<0.01)。试验组44例缓解,对照组6例缓解。结论改善微循环药物联合足量胰岛素注射的作用能够恢复肥胖中青年2型糖尿病患者胰岛素敏感性,多数患者(44/51)可得到缓解。
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关 键 词: | 肥胖中青年 2型糖尿病 蕲蛇酶 胰岛素 微循环 缓解 |
修稿时间: | 2005-04-20 |
The curative effect of lower quantity Acutase Injection combined with enough quantity insulin in treatment of Type 2 diabetes of obese adultescent |
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Abstract: | Objective To probe the methods of improving effects of tiny circulating drug combined with enough insulin injection to recover or strengthen insulin sensitivity, so as to raise curative effect of diabete of obese adultescent. Methods Experiment group was subjected to lower quantity Acutase Injection combined with enough quantity insulin to inject taking orally Dimethylbiguamide plus lower quantity insulin injection as the matched control.In two groups 11 index sign of pre- and post- treat-ment were checked up.Results The difference of experiments 7 index signs and 4 chaperonages performance index sign which had relation with insulin sensitivity and matched control group showed the marked difference meaning(P<0.01).In experiment group 44 cases alleviated,but in matched control group 6 alleviated.Conclusion Im-proving the effects of tiny circulation durg combined with quantity insulin injection can recover diabetics insulin sensitivity of obese adultescent patients, most patients (44/51) can get to alleviation. |
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Keywords: | Obese adultescent Type 2 diabetics Acutase Insulin Tiny circulation Alleviation |
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